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Description

Lactylation of PKM2 at K62 in M1 macrophages inhibits its nuclear translocation, continuously activates glycolysis, and promotes the release of IL-1/TNF-, driving inflammatory progression (88)

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The missing 7 hydrogen bonds are mostly at the end of the 1-strand (in the region around residues 23-29)

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Supplement First is an Authorized Retailer for Douglas Laboratories

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Grimes, J.L

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When your cells are under high levels of oxidative stress, they may become less responsive to insulin

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